This is a subject I've spent a ton of time and research on. I have a 2021 H2 Carbon that I bought brand new. The first set of mods done by my tuner, Midwest Performance & Tuning included a Woolich ECU flash and the installation of a Dynojet Power Commander as well as several other mods.
The bike didn't run right and was very glitchy. After a lot of tunes, retunes, blood, sweat, tears, and swearing we found out from Dynojet that they do not manufacture a Power Commander for an H2 built after 2018! The engine wiring, as well as other things changed in 2019. Turns out the supplier sent us a Power Commander for a 2018 thinking it would work... WRONG. I spoke to Dynojet several times trying to get them to manufacture a Power Commander. It seems unthinkabke that they do no make a Power Commander for the H2 given its status as the pinnacle of sports bikes in the world. Dynojet said they couldn't get there hands on a newer H2. I offered by bike but nothing ever came of it.
However, there is a silver lining. There is a way to reprogram your "Rain Mode" in the ECU and remap its settings to mimick a Dynojet Power Commander. I just added H2R cams to my H2 and at the same time had them remap the rain mode to use MXRO2 fuel. On the dyno it worked. I haven't put it to the test on the street yet.
Good luck with your mods!